The intertwined lives of two kindred souls with ambition begins when Captain Whip Hoxworth discovers that Nyuk Tsin has been smuggled aboard as part of cargo on The Carthaginian, which he captains, a cargo supposed to consist of only male Chinese workers bound for Hawaii. Nyuk Tsin was kidnapped from her Haaka village to be sold to a Honolulu brothel. She is spared when Mun Ki claims she is his wife, and Hoxworth goes along with his wife's suggestion that they can work in the Hoxworth household as domestic servants. Nyuk Tsin becomes known to all as Wu Chow's Auntie (Aunt of Five Continents) when her five sons are named after continents (with Mun Ki's wife in China regarded as their official mother). Whip founds an empire in pineapples, using Japanese laborers, after smuggling his first seed crop from French Guiana as Wu Chow's Auntie grows a family business in Honolulu around her sons.

Train with medical supplies and small U.S. Army unit is heading through Rocky mountains towards plagued Fort Humboldt. Among its passengers are territory governor, priest, doctor and U.S. Marshal with his prisoner, John Deakin. However, nothing on that train is what it seems.